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Pen into the brain is certainly doable if the entry point was through the nasal cavity or an eye socket.
Freeman put his ice pick in people's frontal lobes by going over the globe of the eye. Zap the patient with electroshock to knock him or her out, drive the ice pick in, and sweep it side-to-side and front-to-back to destroy the connections between the frontal lobe and the rest of the brain. Et voilá: another successfully completed pre-frontal lobotomy.

--Al
 
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